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Report on smoker’s face lines treatment through Dermoelectroporation

Dr. A.Gessati*,

*Aesthetic medicine Doctor, Milan, Italy.

Preliminary Study

Dermoelectroporation, well known and established method for transdermal substances delivery without the use of needles, promote the opening of membrane channels and allows the transdermal delivery of Hyaluronic acide based bio revitalizing and growth factor cocktails.
The LED stimulation provokes , due to a controlled , low intensity, ionizing light radiation, a biological response from the treated tissues. The procedure consists of a skin-compatible proteins transdermal delivery to improve the cellular cleaning and the restoration of microcirculation pathways in order to get a fast improvement on the external skin tissues.

Study Design

10 patients were treated on 5 sessions - once per week.
Follow up after one month
Revitalase (Mattioli engineering -Italy)
Ultrapeel® Transderm® Meso System
15mins application each session (AVG).
Treated areas : Per oral area.

Materials and Methods

Materials

Revitalase (Mattioli engineering)
Ultrapeel® Transderm® Meso System(Mattioli engineering)
L.E.D. Photo Stimulation device

Methods

Pre-Sterilised corundum crystals Microdermabrasion up to reach a strong
hyperemia.
Transdermal delivery of 3cc Revitalase – (
Hyaluronic acid enriched by Tissue Growth Factors)cocktail
LED Photo-biomodulation 633+/-6 nm.
1 session per week for a total of 5 sessions depending on the single patient.
Follow up after 1 month.

Results

Significant decreasing of the patient’s smoker’s lines on the selected areas.
Result Assessment : Good according to single
patient’s satisfaction grade.

Conclusions

The present study proved the transdermal delivery of Revitalase through Ultrapeel® Transderm® Meso System is safe, possible and effective.
The administer therapy is:
- Easy to perform.
It doesn’t show up any problem either during or after the administration
It is well tolerated by the patient.
This methodology:
- non invasive.
- Pain Free.
- No side effect reported.

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