Dr. Suneil Jain, N.M.D.

Scottsdale Natural Medicine and Healing Clinic, LLC, 8390 E. Via de Ventura Blvd. Suite F-111 Scottsdale, AZ 85258

Preliminary Study

To evaluate the safety, tolerability and effectiveness of transdermal delivery of a fat reduction cocktail
on abdomen, lateral thigh, medial thigh & back through Dermoelectroporation®.

Study Design

• Toning, not obesity grade treated
• Treatments should be administered every 2 weeks.
  Average number of treatments 3-4.
• L-Carnitine/Phosphatidylcholine cocktail was delivered
• Ultrapeel® Transderm® Meso System
• Session number depending on the single patient’s condition
• Study conclusion on 90% or more resolution of the affected sites

Materials and Methods

Materials

1. L-Carnitine – plays an important role in fat metabolism; shuttles long chain fatty acids across the mitochondrial membrane, once inside stimulates beta oxidation
2. Phosphatidylcholine – penetrates the adipose cell, acts as a fat emulsifier by altering the stored lipids making them water soluble
3. Ultrapeel® Transderm Meso® system from Mattioli Engineering

Methods

• Transdermal delivery of the cocktail through Dermoelectroporation® technology:
• 2 Steps Procedure:
  a)Microdermabrasion
  b) When targeting adipose tissue:
  Transdermal delivery of the cocktail through Ultrapeel® Transderm Meso® system. In this way:
  Delivered every 1-2 weeks until desired result is achieved .Prepare solution using (2) 10 cc syringes.
  Use one syringe per respective side. Per 10 cc
  syringe:
  4 cc L-carnitine 500 mg/mL
  6 cc Phosphatidylcholine 100 mg/mL.

Application of proper follow up at the end.

Results & Conclusions

• Patients were treated with the following results: Patients drastically reduced inches in weeks.
• Transdermal delivery is possible and safe with no contraindications reported.
• All patients showed a good level of improvement and she was so happy with results.