Through Dermoelectroporation, the one and most innovative method for transdermal delivery of water based active ingredients into the body without needles, very important results have been achieved when fighting skin imperfections, elder and actinic keratosis normally cancelled using surgery.All our experiences in treating Actinic keratosis thru Dermoelectroporation have been carried out through the dose of a microdermabrader (till medium Hyperemia) and Transdermal delivery of skin regeneration ingredients (Placentex Mastelli), amino acids, Hyaluronic acid normally injected by syringes, driven through Transderm endorsing Dermoelectroporation. Technology.